Something worth mentioning is if Color are of type ComputeFloat4 some “never been done before with TFX” stuff will be possible :
Any TFX can be used to directly mix textures which allow lots of interesting things to happen.
The drawback as mentioned by @bjoern is that an extra node is necessary when a simple Color input is needed and obviously this is very often the case. It feels very tedious when you want to patch TFX in a very fluid manner as it adds constantly more clicks and nodes searching in the process.
We are in between this two. But again, this could be solved by the devs god hands on stride’s source.